The war caused large-scale destruction of the civil infrastructure of Ukraine. If a comprehensive and accurate assessment can only be possible after victory or at least after the liberation of the temporarily occupied territories, then a quick assessment of the damage is still necessary. The purpose of the study is to highlight the effectiveness of managing the development of the economy of the regions of Ukraine under martial law. The subject of the study is the effectiveness of managing the economic development of the regions of Ukraine in wartime conditions. Achieving the goal of the work is possible by using such research methods as: computational and analytical; graphic; methods of the dynamics of the effectiveness of managing the development of the regional economy in the conditions of martial law; comparison of the assessment of income and expenses in relation to the budgets of the regions of Ukraine; comparative analysis in determining the main directions for improving the efficiency of managing the economic development of the regions of Ukraine. As a result of working on the example of the city of Kharkiv, it was determined that in the first half of last year, the city budget received 8.2 billion UAH, now – 7.6 billion UAH (it is worth reminding about the currency devaluation itself). A reduction in the expenditure part is more likely – UAH 7.5 billion in the first half of 2021 against the current UAH 5.3 billion in 2022. The field of application of this study is the implementation of the proposed measures in the management of the economies of the regions of Ukraine under martial law, namely: the proposed processes of regulation and stabilization of the development of the economies of the regions of Ukraine should contribute to the acceleration of socio-economic development, the determination of the main priorities for solving important problems according to the innovative and progressive scenario, implementation of a system of urgent, renewable actions to manage the development of the economy of the regions of Ukraine. The conclusions drawn demonstrate that timely solutions will help minimize the problems described above, reduce pressure on the financial system of Ukraine’s regions, in particular on the national currency, and facilitate the process of transition from “manual” to market management, taking into account the requirements of military legislation. This will reduce existing imbalances and bring the economic system to a new, much better level